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Tirzepatide Calculator — Reconstitution & Dose

Concentration, draw volume & U-100 units for 5 mg, 10 mg, 15 mg and 30 mg vials

A free tirzepatide calculator for multi-dose vials. Enter the vial size, the water added (or the labelled concentration) and the dose your prescriber gave you, and it converts milligrams into millilitres and U-100 syringe units. It never suggests a dose, and the licensed pens and single-dose vials do not need it.

Enter your numbers

mg

Total amount in the vial, as printed on its label.

mL

How much water went into the vial. Ready-mixed vial? See the note below the calculator.

Dose unit

Enter the dose from your own records or prescription. This tool never suggests one.

Syringe size (U-100 insulin syringe)

Draw volume on a 1 mL U-100 syringe

Fill in the three fields and the math appears here instantly.

102030405060708090100
Concentration
Per unit mark
per U-100 unit
Draws per vial
at the dose entered

Arithmetic on the numbers you entered. Not a dose recommendation and not medical advice.

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How the Tirzepatide calculator works

Licensed products are single-dose pens and single-dose vials, already in solution. Multi-dose vials are either a ready-mixed solution labelled in mg/mL or a lyophilized powder labelled in milligrams. The quick-fill buttons in the calculator are the vial sizes Tirzepatide is commonly labelled in (5 mg, 10 mg, 15 mg and 30 mg). If yours is different, type it in.

Amounts of Tirzepatide are usually written in milligrams (mg), so the calculator opens in mg.

If your vial is a ready-mixed solution, nothing is reconstituted. Enter any vial size and water volume that give the labelled concentration, for example 10 mg and 1 mL for a 10 mg/mL solution.

For a field-by-field walkthrough and a guide to syringe types, see the main peptide calculator.

Tirzepatide concentration table

Each labelled vial size at the same three round water volumes used across this site. It shows how the arithmetic behaves and is not a suggestion of what to use.

Tirzepatide concentration by vial size and water volume
VialWater addedConcentrationEach mark holds
5 mg vial1 mL5 mg/mL0.5 mg per 10 units
5 mg vial2 mL2.5 mg/mL0.25 mg per 10 units
5 mg vial3 mL1.67 mg/mL0.167 mg per 10 units
10 mg vial1 mL10 mg/mL1 mg per 10 units
10 mg vial2 mL5 mg/mL0.5 mg per 10 units
10 mg vial3 mL3.33 mg/mL0.333 mg per 10 units
15 mg vial1 mL15 mg/mL1.5 mg per 10 units
15 mg vial2 mL7.5 mg/mL0.75 mg per 10 units
15 mg vial3 mL5 mg/mL0.5 mg per 10 units
30 mg vial1 mL30 mg/mL3 mg per 10 units
30 mg vial2 mL15 mg/mL1.5 mg per 10 units
30 mg vial3 mL10 mg/mL1 mg per 10 units

Every row for a given vial holds the same total. To compare volumes for a specific reading, use the BAC water calculator.

The formula, step by step

Concentration (mg/mL) = vial size (mg) ÷ water added (mL)
Volume (mL) = dose (mg) ÷ concentration (mg/mL)
U-100 units = volume (mL) × 100

The “Try example numbers” button uses one fixed rule on every page: the smallest labelled vial, 2 mL of water, and whatever amount lands on the 10-unit mark. The amount is a by-product of that rule and not a typical or suggested Tirzepatide dose.

  • Concentration: 5 mg ÷ 2 mL = 2.5 mg/mL.
  • The 10-unit mark is 10 ÷ 100 = 0.1 mL, which holds 0.1 × 2.5 = 0.25 mg.
  • Run it forwards to check: 0.25 mg ÷ 2.5 mg/mL = 0.1 mL, and 0.1 × 100 = 10 units.

Tirzepatide: general reference

General educational reference for research purposes only. None of it is a recommendation, none of it is medical advice, and none of it is used by the calculator, which works only on the numbers you enter.

Tirzepatide is a single molecule that activates two receptors, GIP and GLP-1. It was developed by Eli Lilly and is an approved prescription medicine, sold as Mounjaro and Zepbound.

The FDA approved Mounjaro in May 2022 and Zepbound in November 2023.

Both brands come as single-dose pre-filled pens. Since 2024 Zepbound has also been sold in single-dose vials, each holding one dose that is already in solution, so nothing is reconstituted.

During the shortage, compounded tirzepatide was widely sold in multi-dose vials, which is where the unit arithmetic on this page applies. The FDA took tirzepatide off its shortage list in October 2024 and confirmed the decision that December, which ended broad compounding.

Class
Dual GIP and GLP-1 receptor agonist, approved medicine
Group
GLP-1 family
Also known as
Mounjaro, Zepbound
Molecular weight
About 4,814 Da
Half-life
About 5 days. The FDA-approved prescribing information gives an elimination half-life of approximately 5 days.
Regulatory status
Approved medicine. Tirzepatide is approved by the FDA and the EMA as a prescription medicine. The licensed pens and single-dose vials are pre-measured and need no calculator. Compounding is now limited to narrow, patient-specific cases.
Labelled vial sizes
5 mg, 10 mg, 15 mg and 30 mg

Arithmetic slips to watch for with Tirzepatide

A single-dose vial is not a multi-dose vial

A licensed single-dose vial holds one pre-measured dose, so there is nothing to work out. The arithmetic on this page is only for multi-dose vials, where the amount drawn up depends on the concentration.

Large vials mean high concentrations

Tirzepatide vials run up to 30 mg. With 1 mL of water that is 30 mg/mL, so 10 units already holds 3 mg. The more concentrated the vial, the more a misreading of a single unit matters.

Units are not milligrams

Units measure volume. The same 10 units holds 0.5 mg at 5 mg/mL, 1 mg at 10 mg/mL and 2 mg at 20 mg/mL. A unit count is only correct for the concentration it was worked out for.

What this page does not do

The calculator performs mathematical conversions only. It does not recommend, suggest or verify any Tirzepatide dose or schedule, it does not say how much water to add, and it does not say what Tirzepatide is for, whether it is safe, or whether it is legal where you live. It is not medical advice, diagnosis or treatment, and Peptrack does not sell, supply or endorse any substance.

Always confirm measurements with a licensed healthcare provider or pharmacist. See the full disclaimer.

Mounjaro and Zepbound are trademarks of Eli Lilly and Company. Peptrack is not affiliated with, or endorsed by, Eli Lilly or any other manufacturer.

Sources

Facts last checked: September 2026. Regulatory status changes, so check the regulator’s own pages for the current position.

Tirzepatide Calculator FAQ

How many units is my tirzepatide dose?

It depends entirely on the concentration of your vial, so there is no single answer. Divide the dose in mg by the concentration in mg/mL to get mL, then multiply by 100 for U-100 units. As an illustration of the arithmetic, 10 units holds 1 mg at 10 mg/mL but 2 mg at 20 mg/mL. The calculator converts the dose your prescriber gave you. It does not tell you what that dose should be.

Do Mounjaro or Zepbound pens and vials need this calculator?

No. The licensed pens and the licensed single-dose vials are pre-measured, so there is nothing to calculate. Follow the instructions that come with the product. This calculator is only relevant to multi-dose vials.

My tirzepatide vial is already a liquid. Do I need to reconstitute it?

No. A ready-mixed vial is labelled with a concentration in mg/mL and nothing is added to it. In the calculator, enter any vial size and water volume that give that concentration, for example 10 mg and 1 mL for a 10 mg/mL solution, then enter your dose.

What is the half-life of tirzepatide, and does the calculator use it?

The FDA-approved prescribing information gives an elimination half-life of approximately 5 days. Half-life plays no part in the calculator’s arithmetic. Tirzepatide is a prescription medicine, so the dose and schedule come from your prescriber. This tool never recommends either.

The same math, with each compound’s own vial sizes and units.

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