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DSIP Calculator — Reconstitution & Dose

Concentration, draw volume & U-100 units for 2 mg and 5 mg vials

A free DSIP reconstitution calculator. Enter the vial size, the bacteriostatic water you added and the amount you want to convert, and it works out the concentration, the draw volume and the U-100 syringe mark. It does the arithmetic on your numbers and never suggests a dose.

Enter your numbers

mg

Total amount in the vial, as printed on its label.

mL

How much water went into the vial.

Dose unit

Enter the dose from your own records or prescription. This tool never suggests one.

Syringe size (U-100 insulin syringe)

Draw volume on a 1 mL U-100 syringe

Fill in the three fields and the math appears here instantly.

102030405060708090100
Concentration
Per unit mark
per U-100 unit
Draws per vial
at the dose entered

Arithmetic on the numbers you entered. Not a dose recommendation and not medical advice.

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How the DSIP calculator works

Lyophilized (freeze-dried) powder in a sealed vial, labelled in milligrams. The quick-fill buttons in the calculator are the vial sizes DSIP is commonly labelled in (2 mg and 5 mg). If yours is different, type it in.

Amounts of DSIP are usually written in micrograms (mcg), so the calculator opens in mcg.

For a field-by-field walkthrough and a guide to syringe types, see the main peptide calculator.

DSIP concentration table

Each labelled vial size at the same three round water volumes used across this site. It shows how the arithmetic behaves and is not a suggestion of what to use.

DSIP concentration by vial size and water volume
VialWater addedConcentrationEach mark holds
2 mg vial1 mL2 mg/mL20 mcg per unit
2 mg vial2 mL1 mg/mL10 mcg per unit
2 mg vial3 mL0.67 mg/mL6.7 mcg per unit
5 mg vial1 mL5 mg/mL50 mcg per unit
5 mg vial2 mL2.5 mg/mL25 mcg per unit
5 mg vial3 mL1.67 mg/mL16.7 mcg per unit

Every row for a given vial holds the same total. To compare volumes for a specific reading, use the BAC water calculator.

The formula, step by step

Concentration (mg/mL) = vial size (mg) ÷ water added (mL)
Volume (mL) = dose (mg) ÷ concentration (mg/mL)
U-100 units = volume (mL) × 100

The “Try example numbers” button uses one fixed rule on every page: the smallest labelled vial, 2 mL of water, and whatever amount lands on the 10-unit mark. The amount is a by-product of that rule and not a typical or suggested DSIP dose.

  • Concentration: 2 mg ÷ 2 mL = 1 mg/mL.
  • The 10-unit mark is 10 ÷ 100 = 0.1 mL, which holds 0.1 × 1 = 0.1 mg (100 mcg).
  • Run it forwards to check: 0.1 mg ÷ 1 mg/mL = 0.1 mL, and 0.1 × 100 = 10 units.

DSIP: general reference

General educational reference for research purposes only. None of it is a recommendation, none of it is medical advice, and none of it is used by the calculator, which works only on the numbers you enter.

DSIP is a peptide of nine amino acids. Its full name, delta sleep-inducing peptide, describes the experiment it was discovered in, not an established effect in people. Its international nonproprietary name is emideltide.

It was isolated in 1977 by the Schoenenberger and Monnier group in Basel, from the blood of rabbits. Decades later its gene and its receptor had still not been identified, and a 2006 review in the Journal of Neurochemistry called it “a still unresolved riddle”.

It breaks down quickly. In laboratory tests in plasma its half-life is about 15 minutes, because enzymes clip amino acids from one end.

It has not been approved as a medicine by any major regulator.

Class
Nine-amino-acid neuropeptide
Group
Short peptides (3 to 9 amino acids)
Also known as
Delta sleep-inducing peptide, Emideltide
Molecular weight
About 849 Da
Half-life
About 15 minutes in laboratory plasma tests. In vitro studies report a half-life of roughly 15 minutes in plasma, and it is thought to be shorter still in the body. No human pharmacokinetic study of injected DSIP is available.
Regulatory status
Not approved as a medicine. DSIP is not approved as a medicine by the FDA, the EMA or any other major regulator. Its position in US pharmacy compounding changed in 2023 and again in 2026 and remains under FDA review, so check the FDA’s current bulk drug substances lists.
Labelled vial sizes
2 mg and 5 mg

Arithmetic slips to watch for with DSIP

Two names on the label

DSIP and emideltide are the same compound. A vial labelled with either name is handled identically, and the arithmetic does not change.

Small vials, small numbers

With 2 mL of water a 2 mg vial is 1 mg/mL, or 10 mcg per unit on a U-100 syringe, and a 5 mg vial is 2.5 mg/mL, or 25 mcg per unit. Low concentrations make small amounts easier to read on the scale.

What this page does not do

The calculator performs mathematical conversions only. It does not recommend, suggest or verify any DSIP dose or schedule, it does not say how much water to add, and it does not say what DSIP is for, whether it is safe, or whether it is legal where you live. It is not medical advice, diagnosis or treatment, and Peptrack does not sell, supply or endorse any substance.

Always confirm measurements with a licensed healthcare provider or pharmacist. See the full disclaimer.

Sources

Facts last checked: September 2026. Regulatory status changes, so check the regulator’s own pages for the current position.

DSIP Calculator FAQ

How do I calculate DSIP concentration after reconstitution?

Divide the milligrams in the vial by the millilitres of water added. A 5 mg vial with 2 mL of bacteriostatic water is 2.5 mg/mL, or 25 mcg per unit on a U-100 syringe. A 2 mg vial with the same 2 mL is 1 mg/mL, or 10 mcg per unit. These figures illustrate the arithmetic and are not a suggestion of what to use.

Are DSIP and emideltide the same thing?

Yes. Emideltide is the international nonproprietary name for delta sleep-inducing peptide. They are the same nine-amino-acid compound, so the calculation is identical whichever name is on the vial.

What is the half-life of DSIP?

In laboratory tests in plasma it is roughly 15 minutes, and it is thought to be shorter still in the body. No human pharmacokinetic study of injected DSIP is available. Half-life plays no part in the calculator’s arithmetic.

Is DSIP approved, and does this calculator recommend a dose?

DSIP is not approved as a medicine by the FDA, the EMA or any other major regulator. This calculator never recommends, suggests or checks a dose. It converts the numbers you enter, for research and informational reference only, and it is not medical advice.

The same math, with each compound’s own vial sizes and units.

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