How the Epithalon calculator works
Lyophilized (freeze-dried) powder in a sealed vial, labelled in milligrams. The quick-fill buttons in the calculator are the vial sizes Epithalon is commonly labelled in (10 mg and 50 mg). If yours is different, type it in.
Amounts of Epithalon are usually written in milligrams (mg), so the calculator opens in mg.
For a field-by-field walkthrough and a guide to syringe types, see the main peptide calculator.
Epithalon concentration table
Each labelled vial size at the same three round water volumes used across this site. It shows how the arithmetic behaves and is not a suggestion of what to use.
| Vial | Water added | Concentration | Each mark holds |
|---|---|---|---|
| 10 mg vial | 1 mL | 10 mg/mL | 1 mg per 10 units |
| 10 mg vial | 2 mL | 5 mg/mL | 0.5 mg per 10 units |
| 10 mg vial | 3 mL | 3.33 mg/mL | 0.333 mg per 10 units |
| 50 mg vial | 1 mL | 50 mg/mL | 5 mg per 10 units |
| 50 mg vial | 2 mL | 25 mg/mL | 2.5 mg per 10 units |
| 50 mg vial | 3 mL | 16.67 mg/mL | 1.667 mg per 10 units |
Every row for a given vial holds the same total. To compare volumes for a specific reading, use the BAC water calculator.
The formula, step by step
The “Try example numbers” button uses one fixed rule on every page: the smallest labelled vial, 2 mL of water, and whatever amount lands on the 10-unit mark. The amount is a by-product of that rule and not a typical or suggested Epithalon dose.
- Concentration: 10 mg ÷ 2 mL = 5 mg/mL.
- The 10-unit mark is 10 ÷ 100 = 0.1 mL, which holds 0.1 × 5 = 0.5 mg.
- Run it forwards to check: 0.5 mg ÷ 5 mg/mL = 0.1 mL, and 0.1 × 100 = 10 units.
Epithalon: general reference
General educational reference for research purposes only. None of it is a recommendation, none of it is medical advice, and none of it is used by the calculator, which works only on the numbers you enter.
Epithalon, also spelled Epitalon, is a synthetic peptide of four amino acids (Ala-Glu-Asp-Gly). It was designed to mirror epithalamin, an extract of cattle pineal glands.
It came out of a research programme begun in the 1970s by Vladimir Khavinson at what became the St. Petersburg Institute of Bioregulation and Gerontology, and most studies of it were carried out there.
The human studies usually cited for it used the pineal extract, not the synthetic peptide, and independent replication outside Russia is limited.
It has not been approved as a medicine by any major regulator.
- Class
- Synthetic tetrapeptide
- Group
- Short peptides (3 to 9 amino acids)
- Also known as
- Epitalon, AEDG, Ala-Glu-Asp-Gly
- Molecular weight
- About 390 Da
- Half-life
- Not established. No human pharmacokinetic study of Epithalon has been published.
- Regulatory status
- Not approved as a medicine. Epithalon is not approved as a medicine by the FDA, the EMA or any other major regulator. Its position in US pharmacy compounding changed in 2023 and again in 2026 and remains under FDA review, so check the FDA’s current bulk drug substances lists.
- Labelled vial sizes
- 10 mg and 50 mg
Arithmetic slips to watch for with Epithalon
Two spellings, one peptide
Epithalon and Epitalon are the same tetrapeptide, also written AEDG. The spelling on the vial makes no difference to the arithmetic.
10 mg and 50 mg vials are five times apart
With 2 mL of water a 10 mg vial is 5 mg/mL, so 10 units on a U-100 syringe holds 0.5 mg. A 50 mg vial in the same 2 mL is 25 mg/mL, so 10 units holds 2.5 mg.
Milligram amounts can exceed the syringe
An amount written in whole milligrams, drawn from a weak solution, can be a larger volume than a small syringe holds. The calculator warns when the result will not fit the syringe size you selected.
What this page does not do
The calculator performs mathematical conversions only. It does not recommend, suggest or verify any Epithalon dose or schedule, it does not say how much water to add, and it does not say what Epithalon is for, whether it is safe, or whether it is legal where you live. It is not medical advice, diagnosis or treatment, and Peptrack does not sell, supply or endorse any substance.
Always confirm measurements with a licensed healthcare provider or pharmacist. See the full disclaimer.
Sources
- Araj et al. (2025), Overview of Epitalon, highly bioactive pineal tetrapeptide
- BSCG: what is changing with peptide regulation in 2026
Facts last checked: September 2026. Regulatory status changes, so check the regulator’s own pages for the current position.
