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KPV Calculator — Reconstitution & Dose

Concentration, draw volume & U-100 units for 5 mg and 10 mg vials

A free KPV reconstitution calculator. Enter the vial size, the bacteriostatic water you added and the amount you want to convert, and it works out the concentration, the draw volume and the U-100 syringe mark. KPV has never been tested in people, so this page is arithmetic and nothing more.

Enter your numbers

mg

Total amount in the vial, as printed on its label.

mL

How much water went into the vial.

Dose unit

Enter the dose from your own records or prescription. This tool never suggests one.

Syringe size (U-100 insulin syringe)

Draw volume on a 1 mL U-100 syringe

Fill in the three fields and the math appears here instantly.

102030405060708090100
Concentration
Per unit mark
per U-100 unit
Draws per vial
at the dose entered

Arithmetic on the numbers you entered. Not a dose recommendation and not medical advice.

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How the KPV calculator works

Lyophilized (freeze-dried) powder in a sealed vial, labelled in milligrams. The quick-fill buttons in the calculator are the vial sizes KPV is commonly labelled in (5 mg and 10 mg). If yours is different, type it in.

Amounts of KPV are usually written in micrograms (mcg), so the calculator opens in mcg.

For a field-by-field walkthrough and a guide to syringe types, see the main peptide calculator.

KPV concentration table

Each labelled vial size at the same three round water volumes used across this site. It shows how the arithmetic behaves and is not a suggestion of what to use.

KPV concentration by vial size and water volume
VialWater addedConcentrationEach mark holds
5 mg vial1 mL5 mg/mL50 mcg per unit
5 mg vial2 mL2.5 mg/mL25 mcg per unit
5 mg vial3 mL1.67 mg/mL16.7 mcg per unit
10 mg vial1 mL10 mg/mL100 mcg per unit
10 mg vial2 mL5 mg/mL50 mcg per unit
10 mg vial3 mL3.33 mg/mL33.3 mcg per unit

Every row for a given vial holds the same total. To compare volumes for a specific reading, use the BAC water calculator.

The formula, step by step

Concentration (mg/mL) = vial size (mg) ÷ water added (mL)
Volume (mL) = dose (mg) ÷ concentration (mg/mL)
U-100 units = volume (mL) × 100

The “Try example numbers” button uses one fixed rule on every page: the smallest labelled vial, 2 mL of water, and whatever amount lands on the 10-unit mark. The amount is a by-product of that rule and not a typical or suggested KPV dose.

  • Concentration: 5 mg ÷ 2 mL = 2.5 mg/mL.
  • The 10-unit mark is 10 ÷ 100 = 0.1 mL, which holds 0.1 × 2.5 = 0.25 mg (250 mcg).
  • Run it forwards to check: 0.25 mg ÷ 2.5 mg/mL = 0.1 mL, and 0.1 × 100 = 10 units.

KPV: general reference

General educational reference for research purposes only. None of it is a recommendation, none of it is medical advice, and none of it is used by the calculator, which works only on the numbers you enter.

KPV is a peptide of just three amino acids: lysine, proline and valine. They are the last three of the 13 amino acids in the hormone alpha-MSH.

The published work on KPV is laboratory research in cells and animals. There are no human clinical trials, so there is no human safety or pharmacokinetic data at all.

It lacks the part of alpha-MSH that binds the melanocortin receptors, which is why it is treated as a separate compound and not simply a short version of the hormone.

Class
Tripeptide fragment of alpha-MSH
Group
Short peptides (3 to 9 amino acids)
Also known as
Lys-Pro-Val, alpha-MSH (11-13)
Molecular weight
About 342 Da
Half-life
Not established. No human pharmacokinetic study of KPV has been published.
Regulatory status
Not approved as a medicine. KPV is not approved as a medicine by the FDA, the EMA or any other major regulator. Its position in US pharmacy compounding changed in 2023 and again in 2026 and remains under FDA review, so check the FDA’s current bulk drug substances lists.
Labelled vial sizes
5 mg and 10 mg

Arithmetic slips to watch for with KPV

A very light molecule, weighed the same way

KPV is among the smallest peptides sold, about 342 Da. That changes nothing in the arithmetic: the calculator works by weight, so 5 mg is 5 mg whatever the size of the molecule.

Same vial sizes as other peptides, same numbers

With 2 mL of water a 5 mg vial is 2.5 mg/mL, or 25 mcg per unit on a U-100 syringe, and a 10 mg vial is 5 mg/mL, or 50 mcg per unit. Those are properties of the vial size and the water, not of KPV.

What this page does not do

The calculator performs mathematical conversions only. It does not recommend, suggest or verify any KPV dose or schedule, it does not say how much water to add, and it does not say what KPV is for, whether it is safe, or whether it is legal where you live. It is not medical advice, diagnosis or treatment, and Peptrack does not sell, supply or endorse any substance.

Always confirm measurements with a licensed healthcare provider or pharmacist. See the full disclaimer.

Sources

Facts last checked: September 2026. Regulatory status changes, so check the regulator’s own pages for the current position.

KPV Calculator FAQ

How do I calculate KPV concentration after reconstitution?

Divide the milligrams in the vial by the millilitres of water added. A 5 mg vial with 2 mL of bacteriostatic water is 2.5 mg/mL, or 25 mcg per unit on a U-100 syringe. A 10 mg vial with the same 2 mL is 5 mg/mL, or 50 mcg per unit. These figures illustrate the arithmetic and are not a suggestion of what to use.

What is KPV?

KPV is a tripeptide made of lysine, proline and valine, the last three amino acids of the hormone alpha-MSH. The published research on it is in cells and animals, and there are no human clinical trials.

What is the half-life of KPV?

It has not been established. No human pharmacokinetic study of KPV has been published. Half-life plays no part in the calculator’s arithmetic.

Is KPV approved, and does this calculator recommend a dose?

KPV is not approved as a medicine by the FDA, the EMA or any other major regulator, and it has never been tested in human clinical trials. This calculator never recommends, suggests or checks a dose. It converts the numbers you enter, for research and informational reference only, and it is not medical advice.

The same math, with each compound’s own vial sizes and units.

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