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Sermorelin Calculator — Reconstitution & Dose

Concentration, draw volume & U-100 units for 2 mg, 5 mg, 9 mg and 15 mg vials

A free sermorelin reconstitution calculator. Sermorelin usually arrives as a pharmacy-labelled vial with its own instructions, so enter the vial size and the diluent volume from that label, then the dose you were given, and the calculator returns the concentration, the draw volume and the U-100 syringe mark. It never suggests a dose.

Enter your numbers

mg

Total amount in the vial, as printed on its label.

mL

How much water went into the vial. Ready-mixed vial? See the note below the calculator.

Dose unit

Enter the dose from your own records or prescription. This tool never suggests one.

Syringe size (U-100 insulin syringe)

Draw volume on a 1 mL U-100 syringe

Fill in the three fields and the math appears here instantly.

102030405060708090100
Concentration
Per unit mark
per U-100 unit
Draws per vial
at the dose entered

Arithmetic on the numbers you entered. Not a dose recommendation and not medical advice.

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How the Sermorelin calculator works

Usually a lyophilized (freeze-dried) powder in a pharmacy-labelled vial, with the diluent volume stated on the label. The quick-fill buttons in the calculator are the vial sizes Sermorelin is commonly labelled in (2 mg, 5 mg, 9 mg and 15 mg). If yours is different, type it in.

Amounts of Sermorelin are usually written in micrograms (mcg), so the calculator opens in mcg.

A compounded vial comes with its own label and instructions, including how much diluent to add. Use that volume here, not a figure from this page.

For a field-by-field walkthrough and a guide to syringe types, see the main peptide calculator.

Sermorelin concentration table

Each labelled vial size at the same three round water volumes used across this site. It shows how the arithmetic behaves and is not a suggestion of what to use.

Sermorelin concentration by vial size and water volume
VialWater addedConcentrationEach mark holds
2 mg vial1 mL2 mg/mL20 mcg per unit
2 mg vial2 mL1 mg/mL10 mcg per unit
2 mg vial3 mL0.67 mg/mL6.7 mcg per unit
5 mg vial1 mL5 mg/mL50 mcg per unit
5 mg vial2 mL2.5 mg/mL25 mcg per unit
5 mg vial3 mL1.67 mg/mL16.7 mcg per unit
9 mg vial1 mL9 mg/mL90 mcg per unit
9 mg vial2 mL4.5 mg/mL45 mcg per unit
9 mg vial3 mL3 mg/mL30 mcg per unit
15 mg vial1 mL15 mg/mL150 mcg per unit
15 mg vial2 mL7.5 mg/mL75 mcg per unit
15 mg vial3 mL5 mg/mL50 mcg per unit

Every row for a given vial holds the same total. To compare volumes for a specific reading, use the BAC water calculator.

The formula, step by step

Concentration (mg/mL) = vial size (mg) ÷ water added (mL)
Volume (mL) = dose (mg) ÷ concentration (mg/mL)
U-100 units = volume (mL) × 100

The “Try example numbers” button uses one fixed rule on every page: the smallest labelled vial, 2 mL of water, and whatever amount lands on the 10-unit mark. The amount is a by-product of that rule and not a typical or suggested Sermorelin dose.

  • Concentration: 2 mg ÷ 2 mL = 1 mg/mL.
  • The 10-unit mark is 10 ÷ 100 = 0.1 mL, which holds 0.1 × 1 = 0.1 mg (100 mcg).
  • Run it forwards to check: 0.1 mg ÷ 1 mg/mL = 0.1 mL, and 0.1 × 100 = 10 units.

Sermorelin: general reference

General educational reference for research purposes only. None of it is a recommendation, none of it is medical advice, and none of it is used by the calculator, which works only on the numbers you enter.

Sermorelin is the first 29 amino acids of human growth hormone-releasing hormone (GHRH), the shortest fragment that keeps the hormone’s full activity.

The FDA approved it in 1997 under the brand name Geref. The manufacturer stopped selling it in 2008, and in 2013 the FDA formally determined that it had not been withdrawn for reasons of safety or effectiveness.

That history shapes how it is found today. No approved sermorelin product is on the market, and in the United States it is prepared by compounding pharmacies on prescription, which is why it usually comes as a pharmacy-labelled vial.

Geref itself was sold in vials of 0.5 mg and 1 mg, much smaller than the compounded vials in circulation now.

Class
GHRH analog, formerly an approved medicine
Group
Growth hormone and IGF-1 axis
Also known as
GHRH (1-29), Geref
Molecular weight
About 3,358 Da
Half-life
About 11 to 12 minutes. The Geref label gave a half-life of 11 to 12 minutes after either intravenous or subcutaneous administration.
Regulatory status
Formerly approved (United States). Sermorelin was an FDA-approved medicine from 1997 until the brand was discontinued in 2008. No approved product is marketed today. In the United States it is available as a compounded preparation on prescription.
Status in sport
Prohibited at all times under the WADA Prohibited List (section S2), where sermorelin is named among the GHRH analogues.
Labelled vial sizes
2 mg, 5 mg, 9 mg and 15 mg

Arithmetic slips to watch for with Sermorelin

The pharmacy label comes first

A compounding pharmacy states the diluent volume and often the resulting concentration. If the concentration is already printed, the first step is done for you, and the calculator should reproduce the same figure from the vial size and the volume.

Large vials, microgram amounts

A 15 mg vial is 15,000 mcg. With 3 mL of diluent that is 5 mg/mL, or 50 mcg per unit on a U-100 syringe. A 9 mg vial with the same 3 mL is 3 mg/mL, or 30 mcg per unit.

What this page does not do

The calculator performs mathematical conversions only. It does not recommend, suggest or verify any Sermorelin dose or schedule, it does not say how much water to add, and it does not say what Sermorelin is for, whether it is safe, or whether it is legal where you live. It is not medical advice, diagnosis or treatment, and Peptrack does not sell, supply or endorse any substance.

Always confirm measurements with a licensed healthcare provider or pharmacist. See the full disclaimer.

Sources

Facts last checked: September 2026. Regulatory status changes, so check the regulator’s own pages for the current position.

Sermorelin Calculator FAQ

How do I calculate sermorelin concentration after reconstitution?

Divide the milligrams in the vial by the millilitres of diluent added. A 9 mg vial with 3 mL is 3 mg/mL, or 30 mcg per unit on a U-100 syringe. A 15 mg vial with the same 3 mL is 5 mg/mL, or 50 mcg per unit. These figures illustrate the arithmetic. Use the diluent volume stated on your own pharmacy label.

Is sermorelin FDA-approved?

It was. The FDA approved sermorelin as Geref in 1997, and the manufacturer discontinued it in 2008. In 2013 the FDA determined it had not been withdrawn for reasons of safety or effectiveness. No approved product is marketed today, and in the United States it is available as a compounded preparation on prescription.

What is the half-life of sermorelin?

The Geref label gave a half-life of 11 to 12 minutes after either intravenous or subcutaneous administration. Half-life is a property of the compound and plays no part in the calculator’s arithmetic.

Does this calculator tell me what sermorelin dose to take?

No. It never recommends, suggests or checks a dose. Sermorelin is a prescription preparation, so the dose comes from your prescriber. This tool converts the numbers you enter, for informational and record-keeping reference only, and it is not medical advice.

The same math, with each compound’s own vial sizes and units.

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